September 2, 2005

GAY PEOPLE'S CHRONICLE 11

• Flare-ups of hepatitis B virus (HBV) infection: If you have HIV and HBV, your liver disease may suddenly get worse if you stop taking TRUVADA. Do not stop taking TRUVADA unless directed by your healthcare provider

• Kidney problems: If you have had kidney problems or take other medicines that can cause kidney problems, your healthcare provider should do regular blood tests to check your kidneys

• Bone changes: It is not known whether long-term use of TRUVADA causes damage to your bones. If you have had bone problems in the past, talk to your healthcare provider before taking TRUVADA

Changes in body fat have been seen in some people taking anti-HIV medicines. The most common side effects of TRUVADA when taken with other anti-HIV medicines are dizziness, diarrhea, nausea, vomiting, headache, abdominal pain, depression, rash, and gas. Skin discoloration (spots and freckles) may also occur.

Discuss all medicines you take with your healthcare provider and be aware:

• TRUVADA should not be used with Combivir®, EMTRIVA, Epivir, Epivir-HBV®, EpzicomTM, Trizivir®, or VIREAD

• Your healthcare provider may need to follow you more closely or adjust your therapy if you are taking Videx®, Videx EC®, Reyataz®, or KaletraR with TRUVADA

For more information, please visit www.truvada.com or call 1-800-GILEAD-5 (1-800-445-3235) and select option 2. There is additional information about TRUVADA on the next page.

TRUVADA, EMTRIVA, and VIREAD are registered trademarks of Gilead Sciences, Inc. All other trademarks are the property of their respective owners.

GILEAD